Inflammatory Skin Diseases: Acne Vulgaris – Pathology

Key Concepts:

Definition of Acne Vulgaris

Overview of the Common Skin Disorder
Characterized by Non-Inflammatory and Inflammatory Lesions

Pathogenesis of Acne Vulgaris

Role of Androgens in Sebaceous Gland Hyperplasia
Formation of Microcomedones and Comedones
Inflammation Triggered by Propionibacterium acnes

Non-Inflammatory Lesions

Introduction to Comedones: Open and Closed
Description of Microcomedones: Precursors to Comedones

Inflammatory Lesions

Papules, Pustules, and Nodules: Inflammatory Manifestations
Involvement of Immune Response in Inflammation

Factors Contributing to Acne Vulgaris

Genetics, Hormonal Imbalance, and Lifestyle Factors
Impact of Diet, Stress, and Environmental Factors

Clinical Presentation

Variability in Severity: Mild, Moderate, and Severe Acne
Distribution on Face, Chest, Back, and Shoulders

Histopathological Features

Examination of Skin Biopsy Samples
Observation of Sebaceous Hyperplasia, Inflammation, and Scarring

Conclusion: Enhanced Understanding of Acne Vulgaris Pathology for Improved Diagnosis and Treatment Strategies

Keywords: acne vulgaris, inflammatory skin diseases, acne pathophysiology, acne lesions, microcomedones, comedones, papules, pustules, nodules, pathogenesis, histopathology, clinical presentation.