Inflammatory Skin Diseases: Acne Vulgaris – Pathology

Inflammatory Skin Diseases: Acne Vulgaris – Pathology

Key Concepts:

Definition of Acne Vulgaris

• Overview of the Common Skin Disorder
• Characterized by Non-Inflammatory and Inflammatory Lesions

Pathogenesis of Acne Vulgaris

• Role of Androgens in Sebaceous Gland Hyperplasia
• Formation of Microcomedones and Comedones
• Inflammation Triggered by Propionibacterium acnes

Non-Inflammatory Lesions

• Introduction to Comedones: Open and Closed
• Description of Microcomedones: Precursors to Comedones

Inflammatory Lesions

• Papules, Pustules, and Nodules: Inflammatory Manifestations
• Involvement of Immune Response in Inflammation

Factors Contributing to Acne Vulgaris

• Genetics, Hormonal Imbalance, and Lifestyle Factors
• Impact of Diet, Stress, and Environmental Factors

Clinical Presentation

• Variability in Severity: Mild, Moderate, and Severe Acne
• Distribution on Face, Chest, Back, and Shoulders

Histopathological Features

• Examination of Skin Biopsy Samples
• Observation of Sebaceous Hyperplasia, Inflammation, and Scarring

Conclusion: Enhanced Understanding of Acne Vulgaris Pathology for Improved Diagnosis and Treatment Strategies

Keywords: acne vulgaris, inflammatory skin diseases, acne pathophysiology, acne lesions, microcomedones, comedones, papules, pustules, nodules, pathogenesis, histopathology, clinical presentation.